A further case of Hb J-Iran [beta77(EF1)His->Asp] in Muğla, Turkey.
نویسندگان
چکیده
Hb J-Iran [beta77(EF1)His-Asp] is a rare hemoglobin variant, described first in Iran by Rahbar et al. in 1967 . To date, several abnormal hemoglobins have been described from different regions of Turkey . In Turkey, the first Hb J-Iran [beta77(EF1) His-Asp] case was reported by Arcasoy et al. . There are four reported cases from the Turkish population, mostly from our group. These reported cases were from Ankara, Antalya and Muğla . Here, we report the fifth family with two brothers having heterozygous cases of Hb J-Iran [beta77(EF1)His-Asp] from Muğla. These two cases were asymptomatic and detected during screening of the Muğla population.
منابع مشابه
Molecular identification of a rare hemoglobin variant, Hb J-Iran [beta77(EF1)His->Asp], in Denizli province of Turkey.
Hb J-Iran [beta77(EF1)His-Asp], a rare hemoglobin variant that does not present health problems, was reported for the first time in the Turkish population in 1986. Our case is the fourth case reported in Turkey and the first case from the Denizli province.
متن کاملHeterozygote Hemoglobin J Iran in Combination with Hemoglobin H Disease
This is a report concerning a concurrent case of hemoglobin J Iran (Hb J Iran) and Hemoglobin H (Hb H) disease in an Iranian woman. The patient was coincidentally found during the course of routine pre-marital genetic counselling for her son. The diagnosis of heterozygote Hb J Iran for her son, ultimately led to the diagnosis of concurrent Hb J Iran and Hb H disease. The hematological examinati...
متن کاملFirst observation of homozygote Hb Q-Iran (alpha 75 (EF4) Asp-His).
The first observation of homozygote Hb Q-Iran (α1 75(EF4) Asp-His) is presented in this report. The clinical and hematological data of the index case, his father and mother showed that homozygous or heterozygous Hb Q-Iran has no clinical importance.
متن کاملFocal myositis: a rare case report
1Department of Radiology, Muğla Yücelen Hospital, Muğla, Turkey 2Department of Family Medicine, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey 3Department of Internal Medicine, Medical Faculty of Dokuz Eylül University, İzmir, Turkey 4Department of Radiology, Medical Faculty of Muğla Sıtkı Koçman University, Muğla, Turkey 5Department of Radiology, Atatürk Training and Research ...
متن کاملAssociation of Hemoglobin H Disease With Hb J - Iran ( fi 77 His - k Asp ) : Impact on Subunit Assembly
T HE DISTRIBUTION of normal and variant hemogbobins (Hbs) in heterozygotes provides insight into the biosynthesis and assembly of the Hb tetramer. Because one f3 gbobin gene is inherited from each parent, an individual heterozygous for a fi gbobin variant would be expected to have approximately equal bevels of normal and abnormal Hbs. A few fi variants such as E, the Lepores, Knossos, K-Woobwic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Turkish journal of haematology : official journal of Turkish Society of Haematology
دوره 24 1 شماره
صفحات -
تاریخ انتشار 2007